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Tuesday 18 September 2012

XMRV not related to Chronic Fatigue Syndrome

A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus. mBio. 2012; 3: e00266-12.

Download the full-text paper here.

View a Questioning Answers post on this paper here.

Friday 17 August 2012

Vitamin D and autism


Reduced serum concentrations of 25-hydroxy vitamin D in children with autism: relation to autoimmunity. Journal of Neuroinflammation. August 2012.

Download the full-text paper here.

Read a Questioning Answers post on this paper here.

Friday 10 August 2012

Genetic variants and autism


Individual common variants exert weak effects on the risk for autism spectrum disorders. Human Molecular Gentics. July 2012.

Download the full-text here.

Read a Questioning Answers post on SNPs and autism here.

Thursday 28 June 2012

EEGs distinguishing autism?


A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study. BMC Medicine. 10: 64.

Download the full-text paper here.

Read a Questioning Answers post on EEGs and autism here.

Tuesday 12 June 2012

Behavioural phenotypes may vary geographically


Visual analysis of geocoded twin data puts nature and nurture on the map. Molecular Psychiatry. June 2012.

Download the full-text paper here.

Tuesday 8 May 2012

Carnitine biosynthesis and autism


A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism. PNAS. May 2012

Download the full-text article here.

View a Questioning Answers post about this research here.

Wednesday 25 April 2012

Environmental factors and autism?

Several papers to link to all of which are open-access:

Read a Questioning Answers post on some of this research here.

Landrigan P. et al. A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities. Environmental Health Perspectives. April 2012
DOI: 10.1289/ehp.1104285

Sheldon JF. et al. Tipping the balance of autism risk: potential mechanisms linking pesticides and autism. Environmental Health Perspectives. April 2012
DOI: 10.1289/ehp.1104553

Kalkbrenner AE. et al. Maternal smoking during pregnancy and the prevalence of autism spectrum disorders using data from the Autism and Developmental Disabilities Monitoring Network. Environmental Health Perspectives. April 2012
DOI: 10.1289/ehp.1104556

Wayman GA. et al. PCB 95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environmental Health Perspectives. April 2012
DOI: 10.1289/ehp.1104832

Wayman GA. et al. PCB 95 modulates calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environmental Health Perspectives. April 2012
DOI: 10.1289/ehp.1104833

Tuesday 24 April 2012

Reviewing glutathione and autism


The potential role of the antioxidant and detoxification properties of glutathione in autism spectrum disorders: a systematic review and meta-analysis. Nutrition & Metabolism. April 2012.

Download the full-text here.

Read a Questioning Answers post about this paper here.

Friday 20 April 2012

Probiotics for gastrointestinal disorders


A meta-analysis of probiotic efficacy for gastrointestinal diseases. PLoS ONE. April 2012

Download the full-text here.

Read a Gutness Gracious Me post on probiotics here.

Thursday 19 April 2012

Porphyrin metabolism as a biomarker for autism risk?


Disordered porphyrin metabolism: a potential biological marker for autism risk assessment. Autism Research. February 2012.

Download the full-text here.

View a Questioning Answers post on this paper here.

Friday 13 April 2012

Co-morbidity in autism spectrum conditions

The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS ONE. April 2012.

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Read a Questioning Answers post on this paper here.

Thursday 12 April 2012

Autism and epigenetics


A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States. Clinical Epigenetics. April 2012.

Download the full-text paper here.

Read a Questioning Answers post on this paper here.

Monday 9 April 2012

Maternal obesity & diabetes linked to autism?

Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics. April 2012.

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View a post on Questioning Answers about this paper here.

Monday 2 April 2012

Six developmental trajectories for childhood autism?

Six developmental trajectories characterize children with autism. Pediatrics. April 2012.
Download the full-text paper here.

Thursday 22 March 2012

Tryptophan depletion and aggression


The effects of acute tryptophan depletion on reactive aggression in adults with Attention-Deficit/Hyperactivity Disorder (ADHD) and healthy controls. PLoS ONE. March 2012.

Download the full-text article here.

Monday 5 March 2012

Lipid metabolism and autism

The neurobiology of lipid metabolism in autism spectrum disorders. Neuro-signals. 2010; 18: 98-112.
Download the full-text here.

Wednesday 22 February 2012

Homocysteine and heart disease: no link?


Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias. PLoS Medicine. February 2012.
Download the full-text here.

Friday 17 February 2012

Signs of autism in the brain at 6 months?


Differences in white matter fiber tract development present from 6 to 24 months in infants with autism. American Journal of Psychiatry. February 2012.
Download the full-text paper here.

A microbial association with autism

A microbial association with autism. mBio. February 2012.
Download the full-text here.
Read a Questioning Answers post on autism and Sutterella here.

Wednesday 15 February 2012

Does diabetes start in the intestines?


Fatty acid synthase modulates intestinal barrier function through palmitoylation of mucin 2. Cell Host & Microbe. February 2012.
Download the full-text article here.

Thursday 9 February 2012

ADHD in middle-aged adults


A population-based study of Attention Deficit/Hyperactivity Disorder symptoms and associated impairment in middle-aged adults. PLoS ONE. February 2012.
Download the full-text article here.

Sunday 22 January 2012

Vitamin D and the leaky gut


Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier. American Journal of Physiology: gastronintestinal and liver physiology. 2008; G208-G216.

Download the full-text article here.

Read a Questioning Answers post about this paper here.

Sunday 15 January 2012

Specific polysaccharide antibody deficiency and autism

Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): Case study. Journal of Neuroinflammation. January 2012
Download the full-text here.
Link to a Questioning Answers post discussing this paper here.

Tuesday 10 January 2012

Sutterella and autism

Application of novel PCR-based methods for detection, quantitation, and phylogenetic characterization of Sutterella species in intestinal biopsy samples from children with autism and gastrointestinal disturbances. mBio. January 2012
Download the full-text paper here.
Link to Questioning Answers post on this paper here.

Thursday 5 January 2012

Trends in autism research


A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures. Molecular Psychiatry. December 2011.
Download the full-text article here.
Link to Questioning Answers post on this paper here.